Genetic Services, Inc. has been generously acknowledged by some of the dedicated researchers throughout the scientific community that have utilized our services. We sincerely thank these individuals for their hard work which has greatly furthered science and medicine.
Please click on the links below if you would like to learn more about any of these individuals' research.
Neckameyer WS, Bhatt P. Nuerotrophic actions of dopamine on the development of a serotonergic feeding circuit in Drosophila melanogaster. BMC Neur. 2012 Mar 13.
Steiner FA, Talbert PB, Kasinathan S, et al. Cell type-specific nuclei purification from whole animals for genome-wide expression and chromatin profiling. Genome Res. 2012 Jan 4.
Tran DT, Zhang L, Zhang Y, et al. Additional members of the polypeptide GalNAc transferase family are essential for viability in Drosophila. J. Biol. Chem. 2011 Dec 7.
Liu Z, Geisbrecht ER. Moleskin is essential for the formation of the myotendinous junction in Drosophila. Dev. Biol. 2011 Nov 15; 359(2): 176-189.
Pellegrino M, Steinbach N, Stensmyr MC, et al. A natural polymorphism alters odour and DEET sensitivity in an insect odorant receptor. Nature 2011 Oct 27; 478: 511-514.
Valadez-Graham V, Yoshioka Y, Velasquez O, et al. XNP/dATRX interacts with DREF in the chromatin to regulate gene expression. Nucl. Acids Res. 2011 Oct; 1-15.
Nern A, Pfeiffer BD, Svoboda K, Rubin GM. Multiple new site-specific recombinases for use in manipulating animal genomes. PNAS 2011 Aug 23; 108(34): 14198-14203.
Kazemian M, Zhu Q, Halfon MS, Sinha S. Improved accuracy of supervised CRM discovery with interpolated Markov models and cross-species comparison. Nucl. Acids Res. 2011 Jul 16; 39(22): 9463-9472.
Buhl LK. Synaptic structure and function at the Drosophila larval neuromuscular junction: A molecular analysis of complexin and radish. Ph.D. dissertation, Massachusetts Institute of Technology, 2011 Jun.
Bendena WG, Zhang J, Burtenshaw SM, Tobe SS. Evidence for differential biosynthesis of juvenile hormone (and related) sesquiterpenoids in Drosophila melanogaster. Gen. Compar. Endocr. 2011 May 15; 172(1): 56-61.
Beerman RW, Jongens TA. A non-canonical start codon in the Drosophila fragile X gene yields two functional isoforms. Neuroscience 2011 May 5; 181: 48-66.
Rodal AA, Blunk AD, Akbergenova Y, et al. A presynaptic endosomal trafficking pathway controls synaptic growth signaling. JCB 2011 Apr 4; 193(1): 201-217.
Jepson JEC, Savva YA, Yokose C, et al. Engineered alterations in RNA editing modulate complex behavior in Drosophila: Regulatory diversity of adenosine deaminase acting on RNA (ADAR) targets. JBC 2011 Mar 11; 286: 8325-8337.
Yu YV, Li Z, Rizzo NP, et al. Targeting the motor regulator Klar to lipid droplets. BMC Cell Biol. 2011 Feb 24; 12(9): 1-15.
Hampel S, Chung P, McKellar CE, et al. Drosophila Brainbow: a recombinase-based fluorescence labeling technique to subdivide neural expression patterns. Nature Methods 2011 Feb 16; 8: 253-259.
Texada MJ, Simonette RA, Deery WJ, Beckingham KM. Tropomyosin is an interaction partner of the Drosophila coiled coil protein Yuri Gagarin. Exp. Cell. Res. 2011 Feb 15; 317(4): 474-487.
Zhang YW, Arnosti DN. Conserved catalytic and C-terminal regulatory domains of the C-terminal binding protein corepressor fine-tune the transcriptional response in development. Mol. Cell. Biol. 2011 Jan; 31(2): 875-384.
Kleinhesselink K, Conway C, Sholer D, et al. Regulation of hemocytes in Drosophila requires dappled Cytochrome b5. Biochem. Gen. 2011 Jan 30; 49: 329-351.
Biersmith B, Liu Z, Bauman K, Geibrecht ER. The DOCK protein sponge binds to ELMO and functions in Drosophila embryonic CNS development. PLoS ONE 2011 Jan 25; 6(1): e16120.
Martin A. Developing Drosophila melanogaster as a model for aminoglycoside antibiotic toxicity. The McNair Scholars Journal of U. of Washington 2011; 10: 135-148.
Morra R, Yokoyama R, Ling H, Lucchesi JC. Role of the ATPase/helicase maleless (MLE) in the assembly, targeting, spreading, and function of the male-specific lethal (MSL) complex of Drosophila. Epigenetics and Chromatin 2011; 4:6.
Carra S, Boncoraglio A, Kanon B, et al. Identification of Drosophila ortholog of HSPB8: Implication of HSPB8 loss of function in protein folding disease. J. Biol. Chem. 2010 Nov 26; 285: 37811-37822.
Sandu C, Ryoo HD, Steller H. Drosophila IAP antagonists form multimeric complexes to promote cell death. JCB 2010 Sep 20; 190(6): 1039-1052.
Garlena RA, Gonda RL, Green AB, et al. Regulation of mixed-lineage kinase activation in JNK-dependent morphogenesis. J Cell Sci 2010 Sep 15; 123: 3177-3188.
Vos MJ, Zijlstra MP, Kanon B, et al. HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones. Hum. Mol. Genet. 2010 Sep 9; 19(23): 4677-4693.
Croset V, Rytz R, Cummins SF, et al. Ancient protosome origin of chemosensory ionotropic glutamate receptors and the evolution of insect taste and olfaction. PLoS Genet 2010 Aug 19; 6(8): e1001064.
Liu H, Wang JYS, Huang Y, et al. Structural basis for methylarginine-dependent recognition of Aubergine by Tudor. Genes and Dev. 2010 Aug; 24: 1876-1881.
Coffee RL, Tessier CR, Woodruff EA, Broadia K. Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P. 2010 Jul-Aug; 3(7-8): 471-485.
Cho RW, Song Y, Littleton JT. Comparative analysis of Drosophila and mammalian complexins as fusion clamps and facilitators of neurotransmitter release. Mol. Cell. Neurosc. 2010 Jul 30; 45(4): 389-397.
Nelson KS, Furuse M, Beitel GJ. The Drosophila claudin kune-kune is required for septate junction organization and tracheal tube size control. Genetics 2010 Jul; 185(3): 831-839.
Chen K, Gracheva EO, Yu SC, et al. Neurexin in embryonic Drosophila neuromuscular junctions. PLoS ONE 2010 Jun 14; 5(6): e11115.
Funakoshi Y, Negishi Y, Gergen JP, et al. Evidence for an essential deglycosylation-independent activity of PNGase in Drosophila melanogaster. PLoS ONE 2010 May 10; 5(5): e10545.
Basu A, Atchison ML. CtBP levels control intergenic transcripts, PHO/YY1 DNA binding, and pCG recruitment to DNA. J. Cell. Biochem. 2010 May 1; 110(1): 62-69.
Freeman A, Bowers M, Mortimer AV, et al. A new genetic model of activity-induced Ras signaling dependent pre-synaptic plasticity in Drosophila. Brain Research 2010 Apr 22; 1326: 15-29.
Bolinger C, Zasadil L, Rizaldy R, Hildebrand JD. Specific isoforms of Drosophila shroom define spatial requirements for the induction of apical constriction. Dev. Dynamics 2010 Apr 18; 239: 2078-2093.
Martin AC, Gelbart M, Fernandez-Gonzalez R, et al. Integration of contractile forces during tissue invagination. JCB 2010 Mar 1; 188(5): 735-749.
Sorourian M, Betran E. Turnover and lineage-specific broadening of the transcription start site in a testis-specific retrogene. Fly(Austin) 2010 Jan 30; 4(1): 3-11.
Parton RM, Valles AM, Dobbie IM, Davis I. Live cell imaging in Drosophila melanogaster. Cold Spring Harb. Protoc 2010.
Zasadil LM. The characterization of Drosophila shroom. University of Pittsburgh 2010.
Shao W. Testing the role of an Arf GTPase-activating protein dASAP in epithelial cell polarity in the Drosophila embryo. Master’s thesis, University of Toronto, 2010.
Low KH, Edery I, Gunderson S, et al. Thermosensitive splicing of a clock gene and seasonal adaptation. Ph.D. dissertation, Rutgers University, 2010.
Lin X, O’Tousa JE, Duman JG. Expression of two self-enhancing antifreeze proteins from the beetle Dendroides canadensis in Drosophila melanogaster. J. Insect Phys. 2009 Nov 29.
Tian L, Hires SA, Mao T. Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators. Nature Methods 2009 Nov 8; 6: 875-881.
Gummadova JO, Coutts GA, Glossop NRJ. Analysis of Drosophila Clock promoter reveals heterogeneity in expression between subgroups of central oscillator cells and identifies a novel enhancer region. J. Biol. Rhythms 2009 Oct; 24(5): 353-367.
Mattila J. Regulation of growth by Drosophila FOXO transcription factor. Ph.D. dissertation, University of Helsinki, 2009 Sep.
Zuniga A, Hodar C, Hanna P, et al. Genes encoding novel secreted and transmembrane proteins are temporally and spatially regulated during Drosophila melanogaster embryogenesis. BMC Biol. 2009 Sep 22; 7:61.
Ni JQ, Liu LP, Binari R, et al. A Drosophila resource of transgenic RNAi lines for neurogenetics. Genetics 2009 Aug; 182(4): 1089-1100.
Ramachandran P. Cytoskeletal regulation and morphogen signaling during synaptic outgrowth at the Drosophila larval neuromuscular junction: A dissertation. Ph.D. dissertation, University of Massachusetts Medical School Worcester, 2009 Aug 10.
Alone DP, Rodriguez JC, Noland CL, Nash HA. Impact of gene copy number variation on anesthesia in Drosophila melanogaster. Anesthesiology 2009 Jul; 111(1): 15-24.
Laprise P, Lau KM, Harris KP, et al. Yurt, Coracle, Neurexin IV and the Na+, K+-ATPase form of a novel group of epithelial polarity proteins. Nature 2009 Jun 25; 459: 1141-1145.
Rushton E, Rohrbough J, Broadie K. Presynaptic secretion of Mind-the-Gap organizes the synaptic extracellular matrix-integrin interface and postsynaptic environments. Dev. Dyn. 2009 Mar; 238(3): 554-571.
Karpac J, Hull-Thompson J, Falleur M, Jasper H. JNK signaling in insulin-producing cells is required for adaptive responses to stress in Drosophila. Aging Cell 2009 Mar 15; 8(3): 288-295.
Liberman LM, Stathopoulos A. Design flexibility in cis-regulatory control of gene expression: Synthetic and comparative evidence. Dev. Biol. 2009 Mar 15; 327(2): 578-589.
Reich J, Snee MJ, Macdonald PM. miRNA-dependent translational repression in the Drosophila ovary. PLoS ONE 2009 Mar 2; 4(3): e4669.
Kumar V, Alla SR, Krishnan KS, Ramaswami M. Syndapin is dispensable for synaptic vesicle endocytosis at the Drosophila larval neuromuscular junction. Mol. Cell. Neurosci. 2009 Feb; 40(2): 234-241.
Gordon MD, Scott K. Motor control in a Drosophila taste circuit. Neuron 2009 Feb 12; 61(3): 373-384.
Ardehali MB, Yao J, Adelman K, et al. Spt6 enhances the elongation rate of RNA polymerase II in vivo. The EMBO Journal. 2009 Feb 6; 28: 1067-1077.
Benton R, Vannice KS, Gomez-Diaz C, Vosshall LB. Variant ionotropic glutamate receptors as chemosensory receptors in Drosophila. Cell 2009 Jan 9; 136(1): 149-162.
Kunte MM. Analysis of novel regulatory region and function of a young Drosophila retrogene: Dntf-2r. Ph.D. dissertation, The University of Texas at Arlington, 2009.
Vos MJ. Small heat shock proteins: Implications for neurodegeneration and longevity. Ph.D. dissertation, University of Groningen, 2009.
Votruba SM. MicroRNAs in the Drosophila egg and early embryo. Master’s thesis, University of Toronto, 2009.
Low KH, Lim C, Ko HW, Edery I. Natural variation in the splice site strength of a clock gene and species-specific thermal adaptation. Neuron 2008 Dec 26; 60(6): 1054-1067.
Harris KP, Tepass U. Cdc42 and Par proteins stabilize dynamic adherens junctions in the Drosophila neuroectoderm through regulation of apical endocytosis. JCB 2008 Dec 8; 183(6): 1129-1143.
Zhang L, Zhang Y, Ten Hagen KG. A mucin-type O-glycosyltransferase modulates cell adhesion during Drosophila development. J. Biol. Chem. 2008 Dec 5; 283: 34076-34086.
Gonzalez AN, Lu H, Erickson JW. A shared enhancer controls a temporal switch between promoters during Drosophila primary sex determination. PNAS 2008 Nov 25; 105(47):18436-18441.
Lyulcheva E, Taylor E, Michael M, et al. Drosophila pico and its mammalian ortholog lamellipodin activate serum response factor and promote cell proliferation. Dev. Cell 2008 Nov 11; 15(5): 680-690.
Yang JSJ, Bai JM, Lee T. Dynein-dynactin complex is essential for dendritic restriction of TM1-containing Drosophila Dscam. PLoS ONE 2008 Oct 23; 3(10): e3504.
Toda H, Mochizuki H, Flores III R, et al. UNC-51/ATG1 kinase regulates axonal transport by mediating motor – cargo assembly. Genes & Dev. 2008 Oct 10; 22: 3292-3307.
Kwak JE, Drier E. Barbee SA, et al. GLD2 poly(A) polymerase is required for long-term memory. PNAS 2008 Sept 23; 105(38): 14644-14649.
Page SL, Khetani RS, Lake CM, et al. corona is required for higher-order assembly of transverse filaments into full-length synaptonemal complex in Drosophila oocytes. PLoS Genet. 2008 Sept 19; 4(9): e1000194.
Watson MR, Lagow RD, Xu K, et al. A Drosophila model for amyotrophic lateral sclerosis reveals motor neuron damage by human SOD1. J. Biol. Chem. 2008 Sep 5; 283: 24972-24981.
Pfeiffer BD, Jenett A, Hammonds AS, et al. Tools for neuroanatomy and neurogenetics in Drosophila. PNAS 2008 Jul 15; 105(28): 9715-9720.
Tan S, Lyulcheva E, Dean J, Bennett D. Mars promotes dTACC dephosphorylation on mitotic spindles to ensure spindle stability. JCB 2008 Jul 14; 182(1): 27-33.
Chiu JC, Vanselow JT, Kramer A, Edery I. The phosphor-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by doubletime controls the pace of the clock. Genes Dev. 2008 Jul 1; 22(13): 1758-1772.
Yao J, Zobeck KL, Lis JT, Webb WW. Imaging transcription dynamics at endogenous genes in living Drosophila tissues. Methods 2008 Jul; 45(3): 233-241.
Hare EE, Peterson BK, Iyer VN, et al. Sepsid even-skipped enhancers are functionally conserved in Drosophila despite lack of sequence conservation. PLoS Genet. 2008 Jun 27; 4(6): e1000106.
Das A, Base C, Manna D, et al. Unexpected complexity in the mechanisms that target assembly of the spectrin cytoskeleton. J. Biol. Chem. 2008 May 2; 283: 12643-12653.
Ernst CL. Structural and functional dissection of Kekkon5: A putative novel component of cell adhesion machinery. Worcester Polytechnic Institute 2008 Apr 24.
Bosveld F, Rana A, van der Wouden PE, et al. De novo CoA biosynthesis is required to maintain DNA identity during development of the Drosophila nervous system. Hum. Mol. Genet. 2008 Apr 10; 17(13): 2058-2069.
Marek LR, Kotteman MC, Glazer PM, Bale AE. MEN1 and FANCD2 mediate distinct mechanisms of DNA crosslink pair. DNA Repair 2008 Mar 1; 7(3): 476-486.
Eppinga RD, Peng IF, Lin JLC, et al. Opposite effects of overexpressed myosin Va or heavy meromyosin Va on vesicle distribution, cytoskeleton organization, and cell motility in nonmuscle cells. Cell Motil. Cytoskel. 2008 Mar; 65(3): 197-215.
Geisbrecht ER, Haralalka S, Swanson SK, et al. Drosophila ELMO/CED-12 interacts with myoblast city to direct myoblast fusion and ommatidial organization. Dev. Biol. 2008 Feb 1; 314(1): 137-149.
Morra R, Smith ER, Yokoyama R, Lucchesi JC. The MLE subunit of the Drosophila MSL complex uses its ATPase activity for dosage compensation and its helicase activity for targeting. Mol. Cell. Biol. 2008 Feb; 28(3): 958-966.
Bosveld F, van Hoek S, Sibon OCM. Establishment of cell fate during early Drosophila embryogenesis requires transcriptional Mediator subunit dMED31. Dev. Biol. 2008 Jan 15; 313(2): 803-813.
Bosveld F, Rana A, van der Wouden PE. De novo CoA biosynthesis is required to maintain DNA integrity in a Drosophila model of pantothenate kinase-associated neurodegeneration. Ph.D. dissertation, University of Groningen, 2008.
Burtenshaw SM. Characterization of farnesoic acid o-methyltransferase (FAMeT) and juvenile hormone acid methyltransferase (JHAMT) in relation to Drosophila melanogaster juvenile hormone biosynthesis. Master’s thesis, Queen’s University, 2007 Sep.
Li A, Xie Z, Dong Y, et al. Isolation and characterization of the Drosophila ubiquitin ortholog dUbqIn: in vivo interaction with early-onset Alzheimer disease genes. Hum. Mol. Genet. 2007 Aug 18; 16(21): 2626-2639.
Pane A, Wehr K, Schupbach T. Zucchini and squash encode two putative nucleases required for rasiRNA production in the Drosophila germline. Dev. Cell 2007 Jun 5; 12(6): 851-862.
Affleck JG, Walker VK. Transgenic rescue of methotrexate-induced teratogenicity in Drosophila melanogaster. Toxicol. Sci. 2007 May 7; 99(2): 522-531.
Yonekura S, Xu L, Ting CY, Lee CH. Adhesive but not signaling activity of Drosophila N-cadherin is essential for target selection of photoreceptor afferents. Dev. Biol. 2007 Apr 15; 304(2): 759-770.
Tian E, Ten Hagen KG. A UDP-GalNAc: Polypeptide N-acetylgalactosaminyltransferase is required for epithelial tube formation. J. Biol. Chem. 2007 Jan 5; 282: 606-614.
Qi J, Su S, Mattox W. The doublesex splicing enhancer components Tra2 and Rbp1 also repress splicing through intronic silencer. Mol. Cell. Biol. 2007 Jan; 27(2): 699-708.
Barbee SA, Estes PS, Cziko AM, et al. Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P bodies. Neuron 2006 Dec 21; 52(6): 997-1009.
Balagopalan L, Chen MH, Geisbrecht ER, Abmayr SM. The CDM superfamily protein MBC directs myoblast fusion through a mechanism that requires phosphatidylinositol 3,4,5-triphosphate binding but is independent of direct interaction with DCrk. Mol. Cell. Biol. 2006 Dec; 26(24): 9442-9455.
Marek LR, Bale AE. Drosophila homologs of FANCD2 and FANCL function in DNA repair. DNA Repair 2006 Nov 8; 5(11): 1317-1326.
Das A, Base C, Dhulipala S, Dubreuil RR. Spectrin functions upstream of ankyrin in a spectrin cytoskeleton assembly pathway. JCB 2006 Oct 23; 175(2): 325-335.
Guelman S, Suganuma T, Florens L, et al. The essential gene wda encodes a WD40 repeat subunit of Drosophila SAGA required for histone H3 acetylation. Mol. Cell. Biol. 2006 Oct; 26(19): 7178-7189.
Montana ES, Littleton JT. Expression profiling of hypercontraction-induced myopathy in Drosophila suggests a compensatory cytoskeletal remodeling response. J. Biol. Chem. 2006 Mar 24; 281: 8100-8109.
Leibl FLW, Chen K, Karr J, et al. Increase synaptic microtubules and altered synapse development in Drosophila sec8 mutants. BMC Biology 2005 Dec 13; 3: 27.
Ahmad ST. Molecular and genetic studies characterizing the role of Ninag in chromophore biogenesis, role of rhodopsin in maintenance of photoreceptor cell structure, and genome-wide transcript changes during Norpa retinal degeneration in Drosophila. Ph.D. dissertation, Univ. of Notre Dame 2005 Dec.
Brown JL, Grau DJ, Devido SK, Kassis JA. An Sp1/KLF binding site is important for the activity of a Polycomb group response element from Drosophila engrailed gene. Nucleic Acids Res. 2005 Aug 23; 33(16): 5181-5189.
Van Der Bor V, Hartswood E, Jones C, et al. Gurken and the I factor retrotransposon RNAs share common localization signals and machinery. Dev. Cell 2005 July 5; 9(1): 51-62.
Cole SH, Carney GE, McClung CA, et al. Two functional but noncomplementing Drosophila tyrosine decarboxylase genes: Distinct roles for neural tyramine and octopamine in female fertility. J Biol. Chem. 2005 Apr 15; 280(15): 14948-14955.
Zhang C, Williams EH, Guo Y, et al. Extensive phosphorylation of smoothened in Hedgehog pathway activation. PNAS 2004 Dec 28; 101(52): 17900-17907.
Mandal S. Identification of the sit still gene – shaky suspicions about flies, fats, and multiple sclerosis. Worcester Polytechnic Institute, 2009 Apr. 29.
Vos MJ, Kanon B, Bosveld F, et al. Longevity as evoked by different chaperone activities of small heat shock proteins. Aging Cell, Chapter 5: 79-102.
Vos MJ, Zijlstra MP, Kampinga HH. A comparative screen of the human HSPB family of molecular chaperones reveals HSPB7 as a superior suppressor of aggregation of polyglutamine containing proteins. Aging Cell, Chapter 4: 57-78.